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Biomedical Computer Vision (BMCV)

Prof. Dr. Karl Rohr

We develop advanced image analysis methods for computer-based quantification of biomedical images with focus on deep learning methods for cell microscopy image data. A wide spectrum of novel methods has been introduced and successfully employed in different biomedical applications. The Biomedical Computer Vision Group achieved top-ranking results in international competitions on particle tracking and cell tracking. Our work is important to bridge the gap between experimental image data and quantitative modeling.

Research Strategy

The research group Biomedical Computer Vision (BMCV) develops methods and algorithms for computer-based analysis of biological and medical images. A main aim is to derive quantitative information about cellular and subcellular structures from microscopy image data. We have developed a wide spectrum of novel advanced image analysis methods for cell segmentation and tracking, particle detection and tracking, non-rigid image registration, vessel segmentation, and landmark localization comprising deep learning methods, model-based methods, and probabilistic methods. Top-ranking results in international competitions on particle and cell tracking were achieved. The developed methods have been successfully used in different applications to study virus infection, cell migration and division, and the genome architecture in cooperation with biomedical partners, particularly with research groups at BioQuant. Our work is important to bridge the gap between experimental image data and quantitative modeling.

 

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Prof. Dr. Karl Rohr

Selected Publications

MethylBERT enables read-level DNA methylation pattern identification and tumour deconvolution using a Transformer-based model

Jeong Y, Gerhäuser C, Sauter G, Schlomm T, Rohr K, and Lutsik P

Nature Communications 2025


Non-Rigid Registration of Time-Lapse Cell Microscopy Images Improved by a Semi-Incremental Optimization Method

Gao Q and Rohr K

Proc. IEEE International Symposium on Biomedical Imaging (ISBI 2025)


Superadditivity and Convex Optimization for Globally Optimal Cell Segmentation using Deformable Shape Models

Kostrykin L and Rohr K

IEEE Transactions on Pattern Analysis and Machine Intelligence 2023


Latest News

Open Position in BMCV Group
PhD position in biomedical image analysis  
Qi Gao and Karl Rohr Received the IEEE ISBI 2025 Best Paper Award
Award-winning research advances image registration in cell microscopy through semi-incremental optimization  
Publication in IEEE Transactions on Pattern Analysis and Machine Intelligence 2023
BMCV researchers publish SuperDSM, a globally optimal method for cell segmentation, in IEEE TPAMI.